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promyelocytic (M3) acute leukaemia; a variety of individuals Convey an uncommon morphologic spectrum intermediate involving M2 and M3 AML.

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superior charge of ordinary or dystrophic promyelocytes in peripheralblood and in bone marrow; no intracytoplasmic Auer rods; myeloperoxydasereaction beneficial; immunocytochemical detection with the anti-PLZF demonstrates adistinct punctate nuclear distribution from the protein, suggesting itscompartmentalization from the nucleus.

Rapid detection of prognostically important fusion transcripts in acute leukemia using simplified multiplex reverse transcription polymerase chain reaction.

ZBTB16-RARα variant of acute promyelocytic leukemia with tuberculosis: a circumstance report and evaluation of literature.

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Successful allogeneic bone marrow transplantation within a situation of variant acute promyelocytic leukemia with ZBTB16-RARA.

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A scenario of acute promyelocytic leukaemia with strange cytological capabilities and also a ZBTB16-RARA fusion gene.

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Characterization of cryptic rearrangements and variant translocations in acute promyelocytic leukemia.

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the translocation consists of a breakpoint from the zinc fingerregion of PLZF, with fusion of two zinc fingers to the RARa B area toform a 5 PLZF - three RARa fusion gene; the reciprocal five RARa - 3 PLZF genefuses 7 zinc fingers to your RARa region; RARas breakpoint takes place in1- due to thealternative splicing of PLZF gene, two types of PLZF-RARa protein can be detected: